Thiamine or Vitamin B1 is a Water-soluble vitamin that is produced by plants, bacteria and fungi. Animals do not produce thiamine naturally in their bodies, thus they should acquire this from their regular diet. Thiamine’s Former name was aneurin, talking to the adverse neurological effects on the body because of lack of thiamine, and then was later altered to vitamin B1. The popular disease due to the lack of thiamine in the diet is beri-beri, a disease affecting the peripheral nervous system and cardiovascular disease, and Wernicke-Korsakoff syndrome that is characterized by impaired memory, vision changes and ataxia lack of coordination of muscle movements. Wernicke’s encephalopathy is the type of thiamine deficient illness that is prevalent in Western society. There are three Kinds of Beri-beri that could affect the body when the diet is deficient in thiamine or vitamin B1. Dry Beri-beri is distinguished by Peripheral neuropathy, the expression which describes damage to the nerves of the peripheral nervous system that might be caused by nerve disease or from side effects of additional illness.
Wet Beri-beri is similar to dry beri-beri as both are related to peripheral neuropathy together with symptoms of congestive heart failure, mental confusion, muscle atrophy decrease in muscle mass, edema abnormal accumulation of fluid beneath the skin, tachycardia, abnormal heartbeat and cardiomegaly enlarged heart. Infantile Beri-beri affect babies when they are fed with milk that is deficient in witamina b1. They may exhibit signs of pseudo meningitis characterized by stiff neck, headache, and symptoms of meningitis but without the real inflammation of the meninges, symptoms of cardiovascular disease and lack of voice. Our Body stores approximately 25 To 30 mg thiamine and is found highly concentrated in the kidneys, heart, brain, liver and skeletal muscle tissues. Unphosphorylated not containing phosphorus thiamine can be found in milk, the cerebrospinal fluid, plasma and all extracellular fluids.
Derivatives Of thiamine and Enzymes that are dependent on the action of thiamine can be found in most cells of the body, thus, thiamine deficiency may have adverse effects on each body’s organ systems. However, among those organ systems, the circulatory and nervous systems are particularly sensitive to thiamine deficiency, because of their high nitric oxide. Deficiency Of thiamine in the diet can Lead to fatigue of the eyes, various illnesses related to neurodegeneration or the progressive loss of function of the nerves as in Alzheimer’s, Parkinson’s and Huntington’s disease, wasting and finally death. It can be caused by eating a great deal of raw shellfish and ferns, drinking coffee and tea and chewing betel nuts. Yeast and pork would be the richest Origin of thiamine but may also be found in low concentration in several diverse foods. Cereal grains are also an important nutritional source depending on their accessibility. Whole grains are preferred to processed grains in the diet because considerable concentration of thiamine is found in the outer layers of the grain and germ.